In November 2020, the first-ever ALS Canadian best practice recommendations (BPRs) were published in the Canadian Medical Association Journal(CMAJ). Developed over a number of years by a working group of Canadian ALS clinicians, this document represents what specialists in ALS care agree should be the standard of care for any Canadian diagnosed with ALS. Canadians affected by ALS must receive the best possible standard of care regardless of where they live. That is why a pan-Canadian working group of experts in ALS clinical care developed the Canadian ALS Best Practice Recommendations (BPRs). The BPRs reflect the Canadian healthcare system’s reality and addresses issues relevant to Canada, including timeliness of care, disease-modifying therapies, medical assistance in dying (MAiD), and caregiver support. They will empower advocacy for access to the best and most appropriate care for people living with ALS.